Predictors for aki in a cardiac surgery population undergoing cardio-pulmonary bypass

Methods In total, 259 patients were enrolled, after the exclusion of patients with severe pre-existing renal insufficiency (defined as a eGFR< 15 ml/min). As part of a broader study, urine and blood samples were obtained immediately before initiation of cardio-pulmonary bypass. Patients were subsequently retrospectively divided into 2 groups, AKI (n=84) and non-AKI (n=175). This subdivision was based on based on the AKIN criteria i.e. increase in s-Creat ≥ 0.3 mg/dl or ≥ 50% compared to baseline within 48 h or reduction in urine output < 0.5 ml/kg/h for more than 6 h. Statistical analysis of all characteristics before arrival on the ICU was performed.